Prenatal DDT Exposure and Testicular Cancer: A Nested Case-Control Study

Evaluation of exposure to pioglitazone and risk of prostate cancer: a nested case–control study

OBJECTIVES Investigate potential association between pioglitazone exposure and risk of prostate cancer. RESEARCH DESIGN AND METHODS Nested, matched case-control study. UK primary care data (Clinical Practice Research Datalink (CPRD) GOLD) linked to inpatient (Hospital Episode Statistics (HES)) and cancer registry (National Cancer Information Network (NCIN)) data. English men aged ≥40 years di...

Human Exposure to Endocrine-Disrupting Chemicals and Prenatal Risk Factors for Cryptorchidism and Hypospadias: A Nested Case–Control Study

BACKGROUND Exposure to xenoestrogens during pregnancy may disturb the development and function of male sexual organs. OBJECTIVE In this study we aimed to determine whether the combined effect of environmental estrogens measured as total effective xenoestrogen burden (TEXB) is a risk factor for male urogenital malformations. METHODS In a case-control study, nested in a mother-child cohort (n...

Case–Control Study, Nested

Case-control study of anthropometric measures and testicular cancer risk

The etiology of testicular germ cell tumors (TGCTs) is poorly understood. Recent epidemiological findings suggest that, TGCT risk is determined very early in life, although the available data are still conflicting. The rapid growth of the testes during puberty may be another period of vulnerability. Body size has received increasing attention as possible risk factor for TC. To clarify the relat...

Bisphenol a exposure in Mexico City and risk of prematurity: a pilot nested case control study

BACKGROUND Presence of Bisphenol A (BPA) has been documented worldwide in a variety of human biological samples. There is growing evidence that low level BPA exposure may impact placental tissue development and thyroid function in humans. The aim of this present pilot study was to determine urinary concentrations of BPA during the last trimester of pregnancy among a small subset of women in Mex...